行业动态
New arrives, BSBE welcome Christmas and New Year's Day with new launching (first part)
Published：2019-12-25
Source：[英文]世界杯直播
Official Announcement
December 23rd, 2019, Five new products from BSBE
Successfully obtained the product registration certificate, officially launching to the market!
01 Serum amyloid A (SAA)
02 α 1-antitrypsin (AAT)
03 Haptoglobin (HPT)
04 α 1-acid glycoprotein (AAG)
05 HbA1c
SAA
1. Overview
Serum amyloid A (SAA) is the precursor of tissue amyloid A, which belongs to acute phase reaction protein.
2. Clinical significance
2.1 SAA is an index of inflammatory activity, which has both sensitivity and specificity for the diagnosis of bacterial and viral infection. The combined detection of SAA and CRP is helpful for the differential diagnosis of bacterial and viral infection;
2.2 SAA can be used as the risk factor of cardiovascular disease and the auxiliary diagnostic index of amyloid disease.
HPT
1. HPT overview
Haptoglobin (HPT), also known as binding globin, is an acidic glycoprotein in the serum globulin component, which widely exists in human and many mammalian serum and other body fluids, mainly synthesis and degrade in the liver.
2. Clinical significance of HPT
2.1 Decrease or disappearance of haptoglobin: mainly be found in various intravascular hemolytic anemia, such as autoimmune anemia, megaloblastic anemia, etc.
2.2 The increase of haptoglobin: acute and chronic infection, tuberculosis, autoimmune diseases, tumor and taking hormone drugs, haptoglobin will be increased.
AAT
1. AAT overview
α1-antitrypsin (AAT) is the protein with the highest protease inhibitory activity in plasma, and it is the acute phase reaction protein. Its molecular weight is 54 KD.
2. AAT clinical significance
2.1 The concentration is higher than the normal value: inflammatory reaction (such as infection and rheumatoid disease), tissue necrosis, malignant tumor, trauma.
2.2 The concentration is lower than the normal value: the emphysema, hepatitis and cirrhosis of newborn and infant; the cirrhosis, liver cancer and early age (20-30 years old) emphysema.
AAG
1. Overview
α1-acid glycoprotein (AAG) is a typical acute phase reaction protein. AAG is mainly synthesized by liver. It is a glycoprotein with high content and strong acidity in human serum. It contains about 45% sugar and 40KD molecular weight. The content of AAG in normal human body is relatively low.
2. Clinical significance
2.1 The AAG concentration higher than the normal value: AAG increases in infection (inflammation), trauma, burn, operation and acute myocardial infarction. In addition, rheumatoid arthritis and systemic lupus erythematosus can also lead to the increase of AAG content.
2.2 The AAG concentration lower than normal: malnutrition, severe hepatitis, cirrhosis, nephrotic syndrome, liver parenchyma.
HbA1c
1. Overview
Glycosylated hemoglobin (HbA1c) is a stable compound in which the N-terminal valine residues of glucose and hemoglobin β chain are covalently linked.
2. Clinical significance
HbA1c level can reflect the average blood glucose level in the past 2-3 months. It has been used as a gold standard to evaluate the long-term blood glucose control status in clinical practice, and it is also an important basis for clinical decision to adjust the treatment.